Author Sidebar: I originally developed this web page and the flu web page after we kept running into clients and otherdiabetics who were struggling with whether or not to get the flu vaccine. We were also running into people with Type 1 diabetes, Type 1.5 diabetes, other autoimmune diseases; and, also people who had parents with Alzheimer's disease.
During our research, we began to see connections between nutrition, leaky gut, immune dysfunction, and problems with the brain and central nervous system (CNS). That led us to on a journey to research various neurological and neurodegenerative diseases, such as Alzheimer's disease (AD), Amyotrophic lateral sclerosis (ALS), Guillain-Barré syndrome (GBS), multiple sclerosis (MS), Parkinson's disease (PD), and Autism spectrum disorder.
So, about 11 years ago at a medical conference, I was asked whether I thought there was a link between diabetes and Alzheimer's, especially since I had mentioned in my book, Death to Diabetes (published in 2005). When I said "yes", it upset a lot of medical people. But, once I explained the pathology, most of the doctors and medical experts calmed down, but, they still didn't accept my conclusions.
Well, here we are now, 11 years later and, Western Medicine now recognizes and accepts the fact that what I had stated in my book was true -- that Type 2 diabetes can lead to Alzheimer's. In fact, some doctors even refer to Alzheimer's as Type 3 diabetes.
Well, a few years later, I was speaking at another conference about prescription drugs and vaccines; and, I was asked whether I thought there was a link between vaccines and autism. When I said "yes", it upset a lot of medical people. Needless to say, this created a lot of upheaval by the audience ...
Although some doctors have admitted (behind closed doors) that there is a causal relationship between vaccines and autism, a lot more research needs to be done and a lot more medical experts need to step up to the plate and admit that there is an obvious link between autism and vaccines.
What is Autism?
Before we get into this controversial issue, let's step back for a moment and take a look at what exactly is autism. I think that may lend some insight into why this problem has not be solved.
According to Western Medicine, autism is called Autism spectrum disorders (ASD). ASD is a set of neuro-developmental disorders characterized by impaired social interaction and communication, repetitive and stereotyped patterns of behavior, and uneven intellectual development often with intellectual disability.
But, autism is more than a social interaction or psychological behavioral problem -- it is some form of a pathological neurological or neurodegenerative problem resulting in some form of brain damage.
More specifically, at its core, autism is a neurological, neurodevelopmental and neuro-degenerative disease that is partially due to chronic inflammation and excess oxidation from an immune response that causes brain damage. The root causes include viruses, genetics, environmental factors, food chemicals, and toxins such as mercury or aluminum being placed in vaccines.
That may seem harsh and an oversimplification of a complex problem -- I don't mean it that way. It's just that it's clear that there is something wrong with the brain and its development! Anyone who doesn't have an agenda to protect or defend the pharmaceutical companies can see that the child's behavior is due to more than a psychological problem! Instead of classifying autism as simply a psychological disorder, it should be seen as a pathological problem due to brain damage causing a lack of brain development.
In addition, although autism is not classified as an autoimmune disease, it does have some characteristics of autoimmune dysfunction because some autistic children have been found to have autoimmune-like pathologies, e.g. allergies, ear infections, skin rashes, leaky gut syndrome, frequent colds, etc.
From a neurological and neurodegenerative perspective, the neurons in the brain are affected, actually harmed or damaged when they are attacked by some foreign invader such as a pathogen or a toxin. When that happens, the neurons release signals called cytokines (or chemokines). These protein signals activate microglia, which are the brain's immune cells.
In order to protect the rest of the brain, these microglia trigger a cascade of inflammatory immune responses to destroy the specific neurons that have been damaged by the foreign invader -- in this case, it's either mercury or aluminum -- both of which are well-known neurotoxins.
Normally, this kind of "damage control" would be enough to protect the brain from further damage. But, if the brain is subjected to more toxins from more vaccines before the current toxins can be "cleared", this will continue to fuel the inflammation and spread the damage to other regions of the brain.
Now, the vaccines are not the only problem here. If there are other health issues or disease pathologies (such as leaky gut or a viral infection), they can fuel the inflammation in the brain and cause it to create more damage in a specific region of the brain or cause the damage to spread to additional regions of the brain. This form of systemic inflammation is like adding gasoline to a fire.
If autism were seen as a problem associated with brain damage, then, medical experts and researchers could focus on finding the root causes of the brain damage and why the brain has not developed properly.
Just to be clear: The "brain damage" early on is due to the lack of the various regions of the brain becoming developed as part of the normal growth and development process because the microglia are activated in a M1 pro-inflammatory mode. But, with the proper nutritional changes, the microglia can be switched from M1 to M2 anti-inflammatory mode to support the development of the various regions of the brain (more about this later).
What's the Harm in a Name?
This may not seem that important to most of you, but, how diseases are named or described by the medical industry is problematic at best. The incorrect description of a disease takes our focus away from understanding the actual root cause(s) of the disease and how to defeat the disease.
For example, when I was diabetic, I was always told that Type 2 diabetes was a "blood sugar" disease. Everyone I met referred to this disease as a blood sugar problem. Experts who had given countless lectures and others who had written hundreds of books about diabetes called it a blood sugar problem. Consequently, all of the diabetes programs out there had come up with supposed "cures" or treatment strategies that focused on lowering your blood sugar as the ultimate goal. But, most of them didn't work. Why?
Because everyone (especially the medical industry) was focused on fixing the symptom associated with the disease instead of the root cause. High blood sugar is a symptom of diabetes -- it is not the root cause! As a result, most people will remain diabetic. If you think about it, it's a genius strategy because it tricks most people into taking diabetic pills and other drugs, which happen to be very good at lowering blood sugar, but, they never fix the problem -- so you become a lifetime customer of the drugs!
Now, what does that have to do with autism? Well, the medical industry describes autism as a social interaction and psychological behavioral problem. The social interaction and psychological behavioral issues represent the symptoms of autism.
And, guess what? Everyone treats autism as a social interaction and psychological behavioral problem! Everyone is focused on addressing just the SYMPTOMS of autism -- no one is focused on addressing the actual root causes of autism!
Now, I realize that I may sound like I'm nitpicking here. But, if you think about all of the diseases -- the drugs for those diseases are designed to treat the symptoms of those diseases and never actually cure the disease. Why? Because if the drug companies provided a cure, they would lose you as a customer of their drugs.
Again, this is genius on the part of the drug companies -- true genius. Very few people, if any, are complaining that the medical industry has yet to provide any kind of cure for any disease! Think about the top diseases -- heart disease, cancer, stroke, diabetes ... not one single cure! With all of that brain power, not one single cure? And, we donate millions of dollars to cancer research and other disease research and not one single cure in all these years? Are you kidding me? Not one single medical expert has solved a single problem for any disease?
The same thing applies to autism. It has been labeled and treated as a social interaction and psychological behavioral problem instead of as a brain damage problem.
So, until we start to see autism in the right light as a disease due to brain damage, this disease will remain in the dark and we will continue to be satisfied with accepting this as a genetic problem that can't be cured.
Think about how the narrative would change if everyone saw autism as a neurological or neurodegenerative disease instead of a behavioral problem? Think about how we can provide hope to parents by letting them know that they can help their child by making nutritional changes to improve their autism, and, in many cases, get rid of the autism!
Unfortunately, the bottom-line here is that most medical experts don't really want to solve this problem with autism. More specifically, the pharmaceutical companies don't want medical experts to solve this problem -- because of the obvious link to drugs -- in this case, vaccines.
This would bring the multi-billion dollar vaccine business down like a house of cards. The pharmaceutical companies and their doctors will do everything in their power to keep this problem from ever seeing the light of day. And, if any doctor says otherwise, they will probably lose their license.
Reasons for Autism Concerns
According to the CDC (2014), about 1 percent of the world population has autism spectrum disorder (ASD), with more than 3.5 million Americans living with autism. The rate of autism in the United States is estimated at 1 in 68 births (CDC, 2014).
Despite the denials from Western Medicine and pro-vaccine people, the vaccine-autism issue continues to be a very controversial issue that needs further investigation for several reasons, including the following:
Increase in Autism: There has been a dramatic increase in the number of children being diagnosed with autism from 1 in every 8,000 children in the 1980s to around 1 in every 1000 children in the mid-1990s, to 1 in every 250 in the mid-2000s to 1 in 110 in 2009 to 1 in 88 by 2012. The epidemic has continued and in 2017, the US National Center for Health Statistics just released the latest rate: 1 in every 36 children. These numbers clearly indicate there is a true epidemic of autism in the United States.
Of course, part of this increase is due to doctors getting better at diagnosing the autism along with the greater awareness of autism by parents, doctors and school administrators. However, to believe that all of the increase is due to better diagnosis and awareness is stretching it a bit.
Autism Misunderstood by Doctors: Despite all of the mounting evidence, medical experts and researchers say that they don't understand how autism is increasing at such an alarming rate. What?
Doctors Blame Genetics: Most doctors shift the blame of autism to the parents by saying that autism is genetic, not realizing that autism is even listed as a possible side effect of vaccines on some of the vaccine inserts. Unfortunately, doctors rarely see these inserts, favoring the pharmaceutical marketing sheets over real science.
FYI: A similar thing happened to me when I surprisingly became diabetic -- the doctors told me it was genetic. I think that was the first time when I started to doubt doctors.
Cause of Autism. There is no one single cause of autism. Blaming autism on genetics and the parents excludes the many other possible root causes and biological factors that can cause autism.
No Research Funding for Autism. Several researchers have mentioned that it is almost impossible to receive funding for autism research. Other researchers and doctors have mentioned that they have been told not to pursue and speak publicly about any vaccine-autism connection. Some researchers and doctors said that their careers and reputations were threatened when they investigated the vaccine-autism connection and found some issues/concerns.
Denial from Medical Industry: There is a lack of a scientific response from Western Medicine explaining the science behind the increase and the actual root causes of autism.
There has been a lack of clinical studies to test the safety or danger in using aluminum in so many vaccines, especially given that aluminum is well-known as a neurotoxin.
Proof from Clinical Studies: Actually, there are studies that demonstrate that aluminum is a neurotoxin that causes damage to the brain. But, because these studies were not funded by the pharmaceutical companies, they tend to get ignored. [http://bit.ly/autism-vaccine-studies]
Aluminum in the Brain: Alzheimer's disease is proof that aluminum can cross the blood-brain barrier (BBB) and be deposited in the brain and cause irreparable damage.
Influence of Gut-Brain Axis: There is a lack of understanding of the gut-brain axis (GBA) and how the brain, gut, and immune system are affected by food, chemicals, compounds, drugs, vaccines, viruses, bacteria, etc.
Immune System Misunderstanding: There is a general misunderstanding of the architecture of the immune system, how the immune system works, and how it is affected by vaccines.
Impact of Comorbidities Overlooked: There are contributing factors that create an inflammatory immune response that may contribute to this pathology, e.g. inflammation, leaky gut, dysbiosis, oxidation, immune dysfunction, etc.
Different Types of Aluminum: Most doctors and pro-vaccine people contend that aluminum is excreted via the kidneys and therefore cannot end up in the brain. But, autopsies actually show that aluminum can end up in the brain. Also, although the aluminum that we consume through food and the environment is normally excreted via the kidneys, the aluminum used in vaccines remains in the body and builds up especially when a child is given multiple vaccines over a short period of years.
Types of Vaccines: There are 2 major types of vaccines which provide different immune responses: (1) live vaccine; and, (2) killed vaccine. A live vaccine causes a Th1 immune response; and, a killed vaccine causes a Th2 response. Each type of vaccine has its advantages and disadvantages. For example, a live vaccine triggers a Th1 response, which creates a more permanent immunity as long as the immune system is strong enough to handle the virus. A killed virus is safer for a person with a weaker immune system but the Th2 response provides onlya temporary immunity and does not activate the killer cells, making the person more susceptible to allergies and infections.
No Accountability or Responsibility from Medical and Pharmaceutical Industries: There is a constant defense of vaccines not being the problem instead of focusing on finding out what is the actual problem!
The pharmaceutical & medical industries are not being held accountable while they rake in billions of dollars in the drug and vaccine business.
The Cover-up: The vaccine industry will make over 39 billion dollars in profits this year, with no foreseeable end in its profit growth. The pharmaceutical industry has the biggest political lobby in the United States; and, it pays more for media advertising than any other industry. By controlling the government and the media, there is no significant or visible voice with any influence that can criticize and affect the abhorrent practices of the pharmaceutical industry.
In the meantime, the public is so clueless to what is going on with the drug industry that when someone complains about prescription drugs or vaccines, they come across as a "nut case" and are ridiculed for saying anything that conflicts with Big Pharma.
If you think about it, the pharmaceutical industry has done an excellent job at keeping us in the dark. More than 64% of Americans take some kind of prescription drug or OTC drug. Interestingly, Americans have a deeper trust in vaccines than they do in prescription drugs. During a class, when I point out to the students that vaccines are part of the pharmaceutical drug business, many of them were surprised or didn't consider a vaccine to be a drug!
Pro-vaxxers vs. Anti-vaxxers: There is a constant fighting between pro-vaxxers and anti-vaxxers to "protect their turf" instead of working together to put pressure on the pharmaceutical & medical industries to find a solution.
Anti-vaccine people (in general) believe that all vaccines are bad while pro-vaccine people (in general) believe that all vaccines are good.
So, who's right? Actually, both sides are wrong -- there are no absolutes when it comes to drugs and vaccines. And, as long as both sides continue to point fingers and not put pressure on the pharmaceutical companies, these companies are not going to invest their time and money to solve the problem!
Using an Engineering Approach to Autism
During the past several years, we have been researching disease pathology, virology, immunology, biology, epidemiology, etiology, etc. to better understand this problem.
In engineering, we learned that if you don't define the problem correctly, you can't solve the problem. And, if you don't do a full root cause analysis that looks at everything, then, again, you can't solve the problem.
Methodology: So, from an engineering perspective, we performed a failure modes & effects analysis (FMEA) and a root cause analysis (RCA) and used several other engineering methodologies and tools to reverse-engineer (RE) the biological processes (e.g. inflammation, oxidation, toxicity, dysbiosis, mitochondrial dysfunction, autoimmunity, etc.). FYI: For more details about our engineering processes and methodologies refer to our engineering web page.
This enabled us to identify several possible science-based scenarios where medical science could better explain how the brain can be affected and damaged by viruses, bacteria, cell inflammation, excess oxidation, dysbiosis, leaky gut, food-based compounds, and toxins such as aluminum and mercury.
p.s. When I mentioned FMEA and RCA to a group of doctors, virologists, other medical personnel and a few pro/anti-vaxxers, they just looked at me like I was from another planet. I looked at everyone and said: "Aren't there any engineers among you? That broke the tension and everyone laughed. :-)
Background: Our Current Perspective
As I have mentioned many times, as engineers, we are taught how to solve problems. So, it's in our DNA to focus on using root cause analysis (RCA) after identifying the problem correctly. Then, we use different methods during RCA (including etiology concepts) to "reverse engineer" various biological processes to figure out whether an "impossible" event or outcome can occur (or not occur) such as autism in children.
So, we defined the problem statement as "There are children with autism." instead of "Aluminum causes autism." Why? Because, the second statement draws a conclusion without any root cause analysis. The second statement also is an emotional statement that pits pro-vaxxers and anti-vaxxers against each other, when, in fact, both sides want the same thing! -- healthy children without autism!
Anti-vaxxers believe that there is a straight-line causal relationship between vaccines and autism. They feel this way because they notice that their children's behavior and personality change right before their eyes, usually after a major vaccine event such as MMR.
On the other hand, pro-vaxxers don't believe that there is a straight-line causal relationship between vaccines and autism because they believe that there would be a lot more children with autism. They also believe that the increase in autism is due to better medical diagnostic tools that are able to identify more children with autism.
However, both groups agree that based on recent brain autopsies of children with autism that there are high levels of aluminum in their brain tissues. There is also agreement that aluminum is a neurotoxin that affects the brain and the nervous system.
Here's where we need the scientists and virologists to step in and do some serious research to figure out what is really going on. We are not virologists, but, based on our limited research, we've discovered that in the majority of the vaccine-autism cases that there are other factors and biological processes in play that contribute to this pathology.
It appears that the majority of these children have two or more comorbidities that could trigger a disorder such as autism.
For example, certain viral infections can easily be acquired during fetal life, infancy or early childhood. They can enter the brain through the nasopharyngeal membranes or induce an autoimmune response against the brain, thereby altering the development of brain function.
These comorbidities include cell inflammation, mitochondrial dysfunction, dysbiosis, leaky gut, oxidative stress, neurotoxicity, detoxification dysfunction (excess toxicity), viral infection, and autoimmune dysfunction.
Unfortunately, most of these comorbidities are not the types of problems that most doctors would explicitly be looking for in a child. In addition, there aren't a clear cut set of medical diagnostic blood tests that doctors could perform that would catch these problems. And, even if the doctors did know how to perform these tests, in most cases, the blood tests would come back negative or ambiguous.
In many ways, these types of problems are the result of a convergence of these invisible and unmeasurable comorbidities and the visible event of a vaccine shot. Both the parents and the doctors are unaware of what is really going on in the child's body, until one day the parent notices a gradual or dramatic change in their child's look, behavior and/or personality.
It's very understandable why this is such a difficult and emotional issues for parents of autistic children. I believe that both anti-vaxxers and pro-vaxxers would agree that they both want safer and more effective vaccines that do not cause any harm to any children. But, instead of looking for a win-win scenario, both sides are dug in and won't budge. Both sides need to unite to put pressure on the medical and pharmaceutical industries to do the research to find out what is really going on.
FYI: We work with a lot of diabetics, who struggle with these specific comorbidities, but, most adults are not affected the way children are because adults have more mature immune systems and brain development that protect them from this specific pathology. Instead, most adults end up struggling with diseases such as heart disease, diabetes, cancer, autoimmune diseases, Alzheimer's, and Parkinson's disease.
Neurodegeneration & Neurological Pathology
Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons. However, in some cases, neurodegeneration can stop at anytime or may only occur for a short period of time. Neurodegeneration usually occurs when there is ongoing chronic neuroinflammation along with excess oxidation (free radical damage).
Neurological relates to the nerves and the nervous system. It is also usually associated with some kind of inflammation.
In addition, depending on the specific disease pathology, there are other biological processes that tend to coexist with neuro-degeneration and neurological including one or more of the following:
- Neural Dysfunction
- Neural Toxicity
- Mitochondrial Dysfunction
- Local Inflammation
- Systemic Inflammation
- Leaky Gut
- Debris Clearance
There are many brain-related, nerve-related, and neuro-degenerative-related diseases, disorders and illnesses that occur as a result of neurodegenerative processes. Some of the more common or well-known neurodegenerative and neurological-related diseases and disorders include:
- Alzheimer's disease (AD)
- Amyotrophic lateral sclerosis (ALS)
- Autism spectrum disorder (ASD)
- Guillain-Barre syndrome (GBS)
- Multiple sclerosis (MS)
- Parkinson's disease
- Peripheral Neuropathy
These diseases result in progressive degeneration and/or death of neuron cells, primarily due to chronic inflammation, excessoxidation and phagocytosing (absorbing) the pathogen or toxin.
In addition, most of these diseases are usually accompanied with some form of systemic inflammation that tends to fuel these diseases, making them very difficult to treat effectively.
These diseases cause significant damage and tend to affect multiple areas and multiple cells associated with the nervous system:
- Central nervous system (CNS), including the spinal cord
- Multiple areas of the brain, e.g. amygdala, cerebrum, cerebellum, hippocampus, brain stem, etc.
- Multiple cells, e.g. neurons (motor neurons, sensory neurons, interneurons), astrocytes, oligodendrocytes, microglia, etc.
- Other body systems
Depending on when these diseases occur can affect the development of the brain and its ability to perform all of its functions. For example, because Alzheimer's disease tends to occur later in life, it does not affect the early development of the brain and the major regions and parts of the brain.
However, since a disorder like autism tends to occur much earlier in life, it can significantly affect the size and development of the brain and its various parts and regions.
This, in turn, affects many of the brain's functions associated with normal child development such as:
- Emotional stability
- Eye contact
- Sensory processing
- Social interactions
However, despite these social and psychological issues, autism is a lot more than a "social" or "psychological" problem -- it is a problem due to brain damage and should be treated as such.
If you look at some of the physiological symptoms associated with autism, some of the symptoms are also characteristic of other neurological and neurodegenerative diseases such as Alzheimer's, Parkinson's and multiple sclerosis. Examples of symptoms include abnormal behavior, lack of muscle coordination, emotional instability, memory issues, personality problems, and sleeping problems.
And, given the dramatic increase in autism, Western Medicine should be focused on finding the root cause and how to prevent this problem instead of blaming the parents' genetics. It's so obvious that autism is at least partially due to brain damage, which has prevented the brain from developing properly.
Another key aspect of autism pathology is that most children with autism have other health issues that tend to go undiagnosed and not treated, including bowel problems, autoimmunity dysfunction, dysbiosis, leaky gut, systemic inflammation, allergies, ear infections, other infections, etc. Interestingly, many of these health issues are associated with a weak immune system, which can be triggered by a combination of genetic factors, environmental factors and vaccines that trigger a Th2-dominant immune response.
Root Causes of Neurodegenerative and Neurological-related Diseases
First of all, there is no one single cause for autism! There are multiple causes! Looking for a single cause creates a blame-game mentality instead of an open approach to solving the problem and finding the actual root causes.
The following diagram depicts many of the root causes and biological processes that can trigger a neurodegenerative or neurological-related disease, illness or disorder.
Examples of these diseases, illnesses and disorders include Alzheimer's disease (AD), Amyotrophic lateral sclerosis (ALS), Autism spectrum disorder (ASD), epilepsy, Guillain-Barré syndrome (GBS), Huntington's disease (HD), multiple sclerosis (MS), Parkinson's disease (PD), peripheral neuropathy, seizures, and strokes.
In most cases, doctors say that the primary causes of these diseases, illnesses and disorders are due to genetics and environmental factors. That's "code" for "I don't know the cause of your disease."
When I was diabetic, the doctors told me that it was genetic and that there was nothing I could do about it. Well, it turned out that there was something that I could do about it. Although most diseases have a genetic component, research shows that by changing your diet, you can turn off some of those genes and improve your health.
Unfortunately, doctors and Western Medicine do not believe in the power of nutrition. When I was diabetic, my endocrinologist told me that I could eat whatever I wanted as long as I kept taking the 4 insulin shots each day.
So, I suggest that you should not listen to your doctor when it comes to nutrition. Why? Because, almost 50% medical schools don't even require that students take a class in nutrition. And, for the schools that do offer a nutrition course, most of the content is out-of-date! So, do your research -- but, stay away from fad diets and look for those nutritional programs that are science-based and actually make sense.
Autism Pathology Overview: Introduction
I am an engineer with a background in cell biology, biochemistry and virology. From attending various medical conferences and seminars and from running various medical training classes for diabetes, heart disease, obesity, autoimmune diseases, flu prevention, etc. we have met and talked to a lot of medical doctors, nurses and other healthcare professionals.
Even though we know that there are almost no classes in medical school about nutrition, we are still a little surprised when we discover that most medical people know very little about nutrition and the powerful impact that nutrition has on so many diseases.
Recently, during our classes about the flu and vaccines, we have discovered that most doctors and other medical personnel are taught very little about the immune system and the brain during medical school. Most doctors are not aware of the architecture of the immune system and how it really works; and, therefore, they have a misunderstanding of the way that vaccines really work!
Out of the 11 systems in the human body, the Immune System is probably the most misunderstood system by most doctors and Western Medicine. And, out of all of the organs in the human body, the brain is probably the least understood organ by mosts doctors and Western Medicine.
Ironically, one of the major diseases/disorders that we know so little about happens to be involved with both the immune system and the brain. Do you know what it is? It's autism. Coincidence?
Now, I am neither a pro-vaccine or anti-vaccine person. I believe in pro-choice and safe, effective vaccines. That helps me to maintain my objectivity and focus on what is the real problem and what may be some possible viable solutions.
Obviously, how autism develops is a very complex set of biological and biochemical processes and events that need a lot of in-depth research. But, there are some undeniable facts:
Autism has increased dramatically. Even if we take into account that we are diagnosing autism better, it's still a problem! (It simply blows my mind when people continue to harp on these weak excuses).
Aluminum is toxic. Aluminum is a well-known as a neurotoxin along with mercury and other heavy metals. Using the excuse that dietary aluminum is ubiquitous in our environment has nothing to do with why there is so much aluminum in the brain of a baby!
Proof from autopsies. Autopsies show that there is a specific type of aluminum in children's brains -- aluminum nanoparticles that come from vaccines.
Amount of aluminum. The amount of aluminum being injected in babies and young children far exceeds the safe levels even recommended by the FDA.
Absorption rate of aluminum. Our bodies absorb less than only 0.3% of orally administered aluminum, with the majority of it being excreted via the kidneys. However, we absorb 100% of the aluminum injected in our arm from a vaccine. Also, this form of aluminum is not as easily eliminated from the body. In fact, it circulates throughout the body and is deposited in the liver, lungs, kidneys, heart, spleen, brain, etc.
Autism has multiple triggers. Autism is not triggered by a single antigen such as aluminum. In most cases, it's a combination of multiple triggers including viruses (which activate the microglia initially), drugs such as antibiotics (which weaken the immune system), multiple vaccines, and systemic inflammation (such as leaky gut).
Autism Pathogenesis: Inflammation, Neurodegeneration & Immune System Dysfunction
Autism is a function of several harmful biological processes, including inflammation, neurodegeneration, excess oxidation, excess toxicity, and immune system dysfunction. Most of these biological processes are associated with many other diseases such as Alzheimer's Parkinson's, and multiple sclerosis.
Here is a simplistic system-level view of how we believe that autism develops -- by reverse-engineering the end state.
Before a neurotoxin such as aluminum (or mercury) triggers an immune response to activate the microglia, other antigens such as a virus or the use of antibiotics for an ear infection have triggered an immune response and have already activated the microglia into an M1 inflammatory mode.
So, by the time the aluminum starts to affect the blood brain-barrier and the brain, the microglia are already in a highly active state due to a virus or some other infection such as an ear inflection or a system inflammatory issue such as leaky gut.
Key Point: So, there are multiple factors involved in a cascade of inflammation and immune responses causing the microglia to remain in a highly activated state, causing and escalating neuronal damage and preventing normal brain development, myelination, synaptic pruning, neuron signaling, neurotransmitter balancing, mitochondria function, ATP production, apoptosis, phagocytosis, debris clearance, etc.
Concerning aluminum, normally, when we ingest aluminum (such as from cooking with aluminum utensils, taking antacids or using deodorant), we absorb less than 0.3% of the aluminum, which is excreted via the kidneys (unless there is some type of kidney dysfunction).
However, when aluminum is injected directly into the arm, we absorb 100% of the aluminum, which stays in the body and is not is not excreted. There is also inflammation at the injection site, which triggers an immune response, attracting macrophages and other immune cells.
Eventually, the aluminum particles circulate around the body and are deposited in various organs and tissues, including the liver, spleen, heart and brain.
Aluminum is well-known as a neurotoxin that is associated with neurotoxicity, neuroinflammation and neurodegeneration associated with diseases such as Alzheimer's disease, Parkinson's disease and multiple sclerosis.
Aluminum causes inflammation and excess oxidative damage to the tight junctions of the blood-brain barrier (BBB). Once these tight junctions (and supporting astrocytes) are damaged, this allows aluminum to travel across the BBB and into the brain and CNS.
Aluminum causes oxidative and inflammatory damage to various parts of each neuron, including the cell membrane, mitochondria, myelin sheaths, astrocytes, axons, and oligodendrocytes.
This neuronal damage leads to harmful biological processes including mitochondrial dysfunction, demyelination, poor signal or lost of signal transmission, the loss of synapse pruning; and, a loss of neurogenesis in the hippocampus.
In addition, this prevents the microglia from being activated fully into the M2 anti-inflammatory and neurodevelopment mode. The lack of M2 microglia prevents brain development in various regions of the brain, including the amygdala, cerebellum, cerebral, cortex, hippocampus, corpus callosum, etc.
This is one of the reasons why it is so important to start a cleanse-detox as soon as reasonably possible! It is imperative to remove the aluminum and any other neurotoxins (such as mercury) to prevent further damage to the CNS and the brain and enable brain development.
Once the BBB has been damaged, not only does this allow aluminum to cross over and wreak damage in the CNS and brain, but, it opens the door (actually, the junctions) to allow other toxins, pathogens and circulating immune cells to cross over or release cytokines that can impact the CNS/brain.
So, if the child has a problem such as leaky gut syndrome or a viral infection, then, foreign protein particles, viruses and/or other invaders can cross the BBB and wreak even more damage within the CNS and the brain.
After several vaccines, the problem escalates even more, creating a cytokine storm of free radical damage and chronic inflammation.
In addition, the immune system is out of balance due to the number of vaccines over-stimulating the Th2 antibody-mediated immune system, while simultaneously suppressing the Th1 cell-mediated immune system. This may trigger an autoimmune response or it may cause vaccinated individuals to become hypersensitive to toxins, allergens and bacteria while not responding to viruses, yeast and cancer.
When a vaccinated child's immune system becomes Th2-dominant, this creates a weakened Th1 portion of the immune system, which prevents the child from being able to fight off infections, bacteria and other viruses.
As depicted in the diagram (below), the Th2 system (blue box) is an antibody-mediated system and the Th1 system (green box) is a cell-mediated system. Normally, a foreign invader such as a bacteria, virus or toxin enters the body via the nose or mouth, which activates the innate immune system (yellow box). But, when you inject a vaccine into the upper arm, it bypasses the innate immune system, which contains all of the killer immune cells.
This is a large reason why we now have an epidemic of children with asthma, eczema, hay fever, food allergies, candida, ear/gum infections, urinary tract infections (UTIs), and leaky gut.
It's not a coincidence that allergies have increased more than 350% over the past 35 years as the number of vaccines given to a child have increased dramatically over that same time period.
During this time, aluminum deposits have accumulated in the brain and started to cause damage to the neurons in the CNS, including the brain. The damaged neurons in the brain trigger an inflammatory immune response from the unique immune cells in the brain, which are called microglia.
The microglia become activated in a neurotoxic pro-inflammatory state (M1) and use multiple mechanisms (e.g. cytokines, oxidants, enzymes, proteins, etc.) to kill any damaged neurons.
The activated microglia may also phagocytose (absorb) the antigen, such as a virus, bacteria or a toxin. In the case of autism, the antigen is a toxin -- aluminum -- which the microglia absorb.
These activated microglia become highly motile, secreting inflammatory cytokines. They migrate to the damaged area, and phagocytose cell debris and/or damaged neurons. The activated microglia also release inflammatory cytokines to recruit more microglia to the site.
Once the threat has been alleviated, the microglia return to the resting or deactivated state. However, if additional toxins via more vaccines end up deposited in the brain or if the body's system inflammation health issues (e.g. leaky gut) are not addressed, then, this will continue to fuel the neuroinflammation and keep the microglia in a highly agitated and over-activated state.
As a result, the microglia will continue to destroy even more damaged neurons and get rid of any damaged synapses, astrocytes and other debris -- causing even more damage to various regions of the brain.
The microglia trigger apoptosis and destroy the damaged neurons and remove damaged synapses in order to stop the spread of brain damage. This is similar to what firefighters do when a house is on fire -- they destroy part of the house to prevent the fire from spreading through and destroying the entire house.
And, even if the cytokines do not kill theneurons, they may still stress the neurons sufficiently to make them susceptible to phagocytosis by the activated microglia.
Brain Regions Damaged by Autism
It should be clear to everyone that part of the pathophysiology of autism is brain damage. Yes, there are other issues associated with genetics, behavioral changes, social interactions, etc. But, for those of you who believe that autism is 100% genetics-related or 100% behavioral/social, the end result is still some form of brain damage!
All you have to do is take a look at the functions that each brain region performs and you can see that in an autistic child, these functions are not being performed! -- that part of the brain is not developed -- that part of the brain is damaged! There is some kind of neuroinflammation, neurological problem in the brain and CNS.
Much like a computer, the brain relies on intricate wiring to process and transmit information. Scientists have discovered that in people with autism, this wiring is faulty, leading to misfiring in the communications between nerve cells (neurons).
In the brain, neurons transmit important messages that regulate body functions -- everything from social behavior to movement to communications to reacting to external stimuli.
Imaging studies have revealed that autistic children have too many nerve fibers, but that they're not working well enough to facilitate communication between the various parts of the brain. Scientists think that all of this extra circuitry may affect brain size. Although autistic children are born with normal or smaller-than-normal brains, they undergo a period of rapid growth between ages 6 and 14 months, so that by about age four, their brains tend to be unusually large for their age. Genetic defects in brain growth factors, environmental factors and toxins may lead to this abnormal brain development.
Scientists have also discovered irregularities in the brain structures themselves, such as in the corpus callosum (which facilitates communication between the two hemispheres of the brain), amygdala (which affects emotion and social behavior), and cerebellum (which is involved with motor activity, balance, and coordination). They believe these abnormalities occur during prenatal development or after a series of vaccines laden with mercury or aluminum.
In addition, scientists have noted imbalances in neurotransmitters -- chemicals that help nerve cells communicate with one another. Two of the neurotransmitters that appear to be affected are serotonin (which affects emotion and behavior) and glutamate (which plays a role in neuron activity). Together, these brain differences may account for autistic behaviors.
So, when the neurons in different regions of the brain are damaged and destroyed, this affects various parts of the brain including:
- Brain stem
- Cerebral cortex
- Corpus callosum
- Frontal and temporal lobes
- Superior temporal sulcus (STS)
Amygdala. The amygdala is a complex structure adjacent to the hippocampus. The amygdala is involved in processing emotions, and fear–learning. After sensory information — sights, sounds, smells, etc. — are processed in the brain's sensory areas, the information is relayed to the amygdala, which acts as a portal to the emotion-regulating limbic system.
Using input from the individual's stored knowledge, the amygdala determines how the person should respond emotionally—for example, with fear (at the sight of a burglar), love (when seeing a boyfriend or girlfriend) or indifference (when facing something trivial).
Messages cascade from the amygdala to the rest of the limbic system and eventually reach the autonomic nervous system, which prepares the body for action. If the person is confronting a burglar, for example, his heart rate will rise and his body will sweat to dissipate the heat from muscular exertion. The autonomic arousal, in turn, feeds back into the brain, amplifying the emotional response.
Brain Stem. The brain stem controls the flow of messages between the brain and the rest of the body, and it also controls basic body functions such as breathing, swallowing, heart rate, blood pressure, consciousness, and whether one is awake or sleepy. The brain stem consists of the midbrain, pons, and medulla oblongata.
Cerebellum. The cerebellum is located behind the top part of the brain stem (where the spinal cord meets the brain) and is made of two hemispheres (halves).
The cerebellum receives information from the sensory systems, the spinal cord, and other parts of the brain and then regulates motor movements. The cerebellum coordinates voluntary movements such as posture, balance, coordination, and speech, resulting in smooth and balanced muscular activity.
The cerebellum is a relatively small portion of the brain -- about ten percent of the total weight, but it contains roughly half of the brain's neurons, which transmit information via electrical signals.
Cerebral cortex. An overload of neural connections typically observed in autistic brains begins early in a baby's development, when key neurons in the brain region known as the cerebral cortex begin to form their first circuits, new research shows.
Cerebrum. The cerebrum is divided into four regions called lobes that control senses, thoughts, and movements. The four lobes are the occipital, temporal, frontal, and parietal lobes. Although each lobe has a different task to perform, they all must work together.
The cerebrum or cortex is the largest part of the brain, associated with higher brain function such as thought and action.
Corpus callosum. This thick band of nerve fibers divides the cerebral cortex lobes into left and right hemispheres. It connects the left and right sides of the brain allowing for communication between both hemispheres. The corpus callosum transfers motor, sensory, and cognitive information between the brain hemispheres.
Hippocampus. This small organ is located within the brain's medial temporal lobe and forms an important part of the limbic system, the region that regulates emotions. The hippocampus is associated mainly with the consolidation of information from short-term memory to long-term memory. The organ also plays an important role in spatial memory that enables navigation.
Frontal and temporal lobes. Typically there are patches of abnormal neurons in the frontal and temporal lobes where the social, emotional, and communication functions are located. The neurons tend to be smaller, more densely packed and have shorter, less developed branches. Consequently, there is less connectivity and less efficient transmission of signals across synapses.
Prefrontal cortex. Usually there are more neurons in select divisions of the prefrontal cortex.
Superior temporal sulcus (STS). The superior temporal sulcus, and often the temporoparietal junction, is a brain region that is important for numerous aspects of social cognition. This region is typically active during tasks of cognitive empathy and perspective-taking. The STS is also important for the detection of social cues including linguistic intonation, faces, trustworthiness, and intention.
When these parts of the brain are damaged, the brain does not develop properly, causing the child to exhibit different behaviors, emotional instability, a lack of eye contact, and poor language and communications skills.
As part of the neurological and/orneurodegeneration pathogenesis, the microglia get rid of the damaged neurons via phagocytosis and debris clearance processes. This prevents the debris from building up in the brain causing even more problems such as autoimmunity dysfunction.
When there is no neuroinflammation, the microglia are activated in the neuroprotective anti-inflammatory state (M2), which enables brain development for the amygdala, cerebellum, cerebrum, hippocampus, and other regions or parts of the brain that are needed for communications, behavior, emotions, and social interactions.
In addition, the anti-inflammatory state supports developmental processes such as synaptic pruning, which includes axon and dendrite pruning, in order to remove unnecessary neuronal structures such as dendrites and axons.
FYI: Synapses are the connections between neurons that transmit chemical messages. When we learn new information and skills, synapses get stronger. We even generate new ones, a process called neurogenesis. During vital periods of cognitive development, we shed old synapses to make room for higher quality connections that can support more complex mental function. This neural spring cleaning is called synaptic pruning.
Pruning allows the proper, more efficient synapse connections to be made and ensure a more efficient transmission of signals in the brain. This is analogous to why you prune a tree so that it will grow properly and not have some of its branches die.
Pruning helps in the process of removing neurons which may have become damaged or degraded in order to further improve the "networking" capacity of a particular area of the brain. Furthermore, it has been stipulated that the mechanism not only works in regard to development and reparation, but also as a means of continually maintaining more efficient brain function by removing neurons by their synaptic efficiency.
Normally, a child's brain loses about half of its synapses, which enables growth in and between brain regions crucial to thinking like an adult. Mostly, we’re talking about the Prefrontal Cortex (PFC), which is heavily involved in the decision-making processes and risk assessment at which older people excel and teens are notoriously awful.
However, autism inhibits synaptic pruning, leaving the brain of an autistic child with too many synapses and no room to grow in and between brain regions. Too many synapses get in the way and prevent the brain from developing strong and efficient synapse connections for efficient signal transmission. Neurons tend to be smaller, more densely packed in certain areas and have shorter, less developed branches.
The anti-inflammatory state also supports neurogenesis so that new neurons can be created. It also supports phagocytosis and debris clearance in order to get rid of dead neurons and prevent them from collecting in the brain.
Now, given these events, why don't all children who get vaccinated develop autism? Well, it turns out that there are other co-factors and biological processes that fuel chronic inflammation in the brain, including the health of the mother, the health of the child, their nutrition, and other medications such as Tylenol and aspirin, which can fuel neuroinflammation.
In addition, because of the Gut-Brain Axis (GBA)), a problem such as dysbiosis or leaky gut syndrome can trigger an inflammatory immune response, which can fuel and increase the inflammation, oxidation and cytokine storm going on in the brain.
This ongoing inflammation, oxidation and cytokine storm goes undetected until it manifest itself as a change in the child's behavior such as blank stares, no social interaction, seizures, etc. This usually occurs when there is damage to parts of the brain, such as the cerebellum, which affects brain development.
This is a clear sign of neurodegeneration due to the damage of various parts of the brain.
Bottomline, part of autism is due to brain damage caused my aluminum nanoparticle toxicity and other co-factors.
Of course, this needs to be investigated further without any hidden agendas. If we were able to figure this out with our limited knowledge, I suspect that there are experts out there who have already figured this out a lot better than we have. But, because of hidden agendas and due to the powerful influences of the pharmaceutical industry, the CDC, AMA and FDA, the science is being ignored or covered up.
Unfortunately, we realize that it would not be financially beneficial to the pharmaceutical industry to have to scrap millions of dollars of vaccines and spend even more money to research and find another adjuvant that would work as well as aluminum. I suspect that they have already tried and failed to find another adjuvant, so they're focusing their efforts on protecting their investment in aluminum.
Gut-Brain Inflammation Connection to Autism
There is a biochemical signaling mechanism between the gut and the brain -- this is known as the gut-brain axis (GBA). The gut-brain axis consists of bidirectional communication between the central and the enteric nervous system, linking emotional and cognitive centers of the brain with peripheral intestinal functions.
This interaction between the gut and brain appears to be bidirectional, namely through signaling from gut-microbiota to brain and from brain to gut-microbiota by means of neural, endocrine, immune, and humoral links.
This bidirectional communication network includes the central nervous system (CNS), both brain and spinal cord, the autonomic nervous system (ANS), the enteric nervous system (ENS) and the hypothalamic pituitary adrenal (HPA) axis.
Consequently, a troubled intestine (such as leaky gut syndrome) can send signals to the brain, just as a troubled brain can send signals to the gut. Therefore, a person's stomach or intestinal distress can be the cause or the product of anxiety, stress, depression or other behaviors. So, if a child happens to have an undiagnosed leaky gut or a compromised immune system, this can affect the brain!
A leaky gut is a condition where the intestinal wall develops microscopic "holes" that allow bacteria, toxins, incompletely digested food proteins and other compounds to leak out of the intestines and into the bloodstream.
When this happens, the immune system mistakes these leaked compounds as foreign invaders and mounts an immune response (attack). This immune response causes chronic inflammation and increased oxidation (free radical damage) that can affect various organs in the body including the brain.
Establishment of normal gut flora in the month of life plays a crucial role in appropriate maturation of a baby's immune system. Hence, babies who develop abnormal gut flora are left with compromised immune systems and are particularly at risk for developing such disorders as ADHD, learning disabilities, and autism -- particularly if they are vaccinated before restoring balance to their gut flora.
Now, some medical experts will say that "leaky gut" is just a theory and that it cannot affect the brain because these compounds or toxins that are leaking out cannot cross the blood-brainbarrier (BBB). Consequently, they will not support any type of diet change nor will they consider doing any research because they believe that they have proven their point.
FYI: The blood-brain barrier (BBB) is the brain-specific capillary barrier that is critical for preventing toxic substances from entering the central nervous system (CNS).
Research suggests that as many as nine out of 10 children with autism also suffer from gastrointestinal problems such as inflammatory bowel disease and leaky gut.
Note: For more information about leaky gut and how to repair it, refer to the leaky gut section on the DTD AIP Nutritional Program web page.
Nutritional Strategy to Reverse and Treat Autism & Other Neurological Diseases
The good news is that most children can recover from mercury and aluminum-vaccine poisoning, but only if it is caught in time.
Fast action is critical, because vaccine-injected aluminum (just like mercury) does tremendous damage to the brain and to the central nervous system over time. If the aluminum (or mercury) is not removed in a timely manner, then recovery might not be possible.
Aluminum poisoning (just like mercury poisoning) for autistic children is a ticking time-bomb that leads to permanent brain damage. Young children are the most receptive to a full recovery.
The nutritional strategy should address detoxification and the elimination of aluminum from the brain and the rest of the body.
Another key component of the nutritional strategy should address repairing the body's cells and tissues in the brain and the gut.
Another key component of the nutritional strategy (if applicable) should address rebalancing the immune system and the Th1-Th2 pathway.
Another key component of the nutritional strategy (if applicable) should address viral infections and getting rid of any virus.
In addition, if applicable, the nutritional strategy should address other possible health issues such as leaky gut, bowel problems, chronic inflammation, excess oxidation, and other harmful biological processes.
This can be accomplished with the consumption of anti-inflammatory foods, use of periodic detoxes, and nutritional supplementation, e.g. Vitamin D3, Vitamin C, turmeric, probiotics, and silica (to help with removing the aluminum).
Vitamin B-12, in the form of methylcobalamin, is known to be helpful for creating and repairing nerves, along with the use of MSM (methylsulfonylmethane). Foods rich in Vitamin B-12 include grass-fed beef, clams, crab, organic eggs, fish, goat cheese, and liver. Foods rich in sulfur include eggs, fish, garlic, meat and cruciferous vegetables.
The intake of saturated fats is essential, since nerve repair cannot take place without them. Use only saturated fats from grass-fed sources such as grass-fed chicken and grass-fed butter. Include organic flax seed oil;and wild-caught salmon for Omega-3 EFAs to reduce inflammation and help with cell repair.
Please Note to Parents: Before removing gluten and sugar, introduce your child to few new foods you want to add to the new diet. In that way, the change will be less traumatic to the child. If you remove one component at a time, your child may react better this way. For example, first remove the gluten (bread, pasta, biscuits, etc.). Then, a week or two later, remove the sugar (soda, candy, pastries, sweets, etc.).
Ideally, you want to start making diet changes with your child as soon as possible to prevent further brain damage. However, it’s never too late to start something good, despite it being ideal to start as soon as possible. Any autistic child, teenager and even adult, can benefit from a healthy gut --even people who are not autistic.
The influence of fungi, parasites, yeast and bacteria that thrive in our gut from eating too many "dead" processed foods is certain. Today, more people are aware that the brain-gut connection is real and that it affects our body and mind, and, consequently, our behavior.
Mainstream physicians and psychiatrists are likely to tell you that it is impossible to heal the gut or any nerve damage, especially damage to the brain neurons. Do not assume this to be true, because it is only true for some cases. Young people, in particular, have excellent chances of nervous system regeneration. Just remember that those same experts told you that vaccines are harmless, and that there is no cure for autism.
Other key foods include: broccoli, kale, spinach, other green vegetables, bone broth, extra virgin coconut oil, extra virgin olive oil, raw butter, garlic, onions, Omega-3 eggs, raw nuts & seeds, wild-caught salmon, grass-fed chicken/turkey, filtered water.
Other key nutritional supplements include: alpha lipoic acid, aloe vera, B-Complex vitamins, cilantro, chlorella, milk thistle, n-acetyl-cysteine (NAC), selenium, spirulina, Vitamin C (camu camu berry), Vitamin D (unprocessed cod liver oil), Vitamin E (mixed tocopherols and tocotrienols).
For more details, refer to the DTD AIP Nutritional Program as a general guide with some slight modifications, based on your child's specific health needs and food sensitivities.
In addition, the avoidance of eating inflammatory and processed foods is critical. Examples include sugar, wheat, gluten, cow's milk, other dairy, fast foods, soda, diet soda, vegetable oils, and animal meat full of antibiotics and growth hormones, etc.
Although this is a very effective and safe nutritional strategy, most doctors willpooh-pooh this nutritional approach. Why? Because most doctors know very little about the impact of superior nutrition, since doctors only take a 3-hour course in medical school about nutrition.
So, parents need to educate themselves about nutrition in order to help their children. Assuming there has been no major damage to the liver and other detox organs, when gluten, milk products, sugar and other food chemicals are removed from the children's diets, most of them enter into a natural process of recycling and detoxing.
During this detoxification period, the children may become very agitated, hyper, angry, or lethargic because their bodies are going through withdrawal similar to what happens to a drug addict. This can be very upsetting to parents, causing them to give in to the children. But, don't! This is just part of the cleanse and detox process!
Usually within a week to ten days, the child will start to look and behave differently, e.g. eye contact, less hyper-activity, less anxiety, more attentive, start talking, etc. So, hopefully, the parents will hang in there with their children through the detox process. The reward certainly outweighs the discomfort of watching the child suffer through the detox process.
The most important next step is education. Begin to educate yourself about disease pathology, nutritional science, cell biology, pathology, pathogenesis, etc. By doing that, when someone proposes a medical or alternative wellness strategy, you'll know whether they're lying to you or telling the truth.
In the meantime, if you need a macronutrient-balanced nutritional program or if have leaky gut, an autoimmune disease, an allergy, or a thyroid problem, get the author's Autoimmune Disease and Natural Treatments book/ebook.
This book addresses how to calm and balance the immune system by identifying what foods to eat and avoid, what key supplements to take, and what immune modulators will help with Th1 dominance and Th2 dominance. This book also addresses how to repair a leaky gut.
In addition, be proactive and prevent the onset of diabetes, heart disease, and other health problems by getting one of the following author's books, which address inflammation, oxidation, toxic load, etc.:
- Death to Diabetes book or ebook.
- DTD Juicing Book/Ebook
- DTD Raw Food Diet Book/Ebook
- DTD Cleanse & Detox Book/Ebook
Note: For information about the immune system and how to strengthen it, refer to the Boost Immune System web page.
For information about autoimmune symptoms, diagnosis and treatment strategies, refer to the Death to Diabetes Blog.
For more details about the operation of the immune system and its cells, also,refer to the Death to Diabetes Blog.
Note: For information about Autoimmune Diseases and Glycobiology, refer to the Death to Diabetes Blog.
Disclaimer: This site does not provide medical advice, diagnosis or treatment.
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